Anaphylaxis in infants with cow's milk protein allergy: clinical aspects
نویسندگان
چکیده
Results It was included 51 infants (31 M) with median age of first anaphylaxis episode at 6 mo (range 0.03-20 mo). Criterion 1 was the most prevalent (36 patients) at anaphylaxis diagnosis followed by criterion 2 (15 patients). Fresh milk was the trigger in 39 patients and dairy products in 12. Anaphylaxis was the first manifestation of CMA in 36 patients. There was recurrence of episodes in 37 patients, and in 46% it was related to intentional exposure. Many parents were unaware of the initial treatment of anaphylaxis (n = 19), 5 reported spontaneous resolution, but few parents reported use of parenteral medication (n=19) and only 5 informed that epinephrine was administered. Specific IgE to cow’s milk was positive in 45/48 with a median of 13.4 kU/L (0.35 to 100 kU/L). Among three patients with ImmunoCAP to milk below 0.35, two had positive results in the second blood sample and the other had positive prick test. Positivity for casein occurred in 43 patients ranging from 0.35 to 100 (median 12.5 KU/L).
منابع مشابه
A New Synbiotic Can Increase Weight Gain in Infants with Cow's Milk Allergy: A Randomized Controlled Trial
Introduction: Cow’s milk protein allergy is the most common food allergy in many countries, with clinical importance in different aspects. Synbiotic, a combination of probiotics and prebiotics, could be effective in the management of this allergy through modulating the immune system and improving the nutritional status. Methods: In this randomized, controlled trial, 32 infants with cow’s milk a...
متن کاملConsensus statement on diagnosis, treatment and follow-up of cow's milk protein allergy among infants and children in Turkey.
The present paper aims to provide experts' consensus on diagnosis and management of cow's milk protein allergy (CMPA) among infants and children in Turkey, based on review of available evidence-based guidelines, publications and experts' clinical experience. The experts agreed that CMPA diagnosis should be based on symptomatic evaluation and diagnostic elimination diet as followed by implementa...
متن کاملAnaphylaxis to diphtheria, tetanus, and pertussis vaccines among children with cow's milk allergy.
متن کامل
Cow's milk protein allergy. A multi-centre study: clinical and epidemiological aspects.
BACKGROUND Due to the age when it becomes apparent and the treatment needed, cow's milk proteins (CMP) allergy requires an accurate diagnosis to avoid labelling infants falsely as allergic and subjecting them to unnecessary diets. The objective of this multi-centre study carried out at the Allergy Units of 14 Children's Hospitals was to discover the epidemiological, clinical and evolutionary ch...
متن کاملCase report: hematemesis could be an unusual presentation of cow's milk protein allergy in children in Egypt.
Cow's milk protein allergy (CMPA) is common in infants with variable clinical presentation including varied gastrointestinal manifestation. Cow's milk protein allergy chiefly, involving occurs in children below the age of 3 years, successful therapy depends on completely eliminating cow's milk proteins (CMP) from the child's diet. Ideally, with the replacement of hypo or an allergenic food. Sym...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2013